JAK2 Exon 12 Mutation Screening Kit
£889.00
The geneMAP™ JAK2 Exon 12 Mutation Screening Kit is designed for the qualitative detection of the six most common mutations within exon 12 of the JAK2 gene, utilizing allele-specific PCR and multiplex real-time PCR technology. This CE-IVD certified kit is compatible with FAM color real-time PCR instruments, employing melting curve analysis for enhanced diagnostic precision. It is particularly valuable for diagnosing polycythemia vera in patients who are negative for the JAK2 V617F mutation, offering superior analytical sensitivity and specificity with a detection limit down to 2% mutant allele.
The geneMAP™ JAK2 Exon 12 Mutation Screening Kit is designed for the qualitative detection of the six most common mutations within exon 12 of the JAK2 gene, utilizing allele-specific PCR and multiplex real-time PCR technology. This CE-IVD certified kit is compatible with FAM color real-time PCR instruments, employing melting curve analysis for enhanced diagnostic precision. It is particularly valuable for diagnosing polycythemia vera in patients who are negative for the JAK2 V617F mutation, offering superior analytical sensitivity and specificity with a detection limit down to 2% mutant allele.
- Allele Specific PCR: Guarantees high specificity and sensitivity in detecting mutations in exon 12 of the JAK2 gene.
- Multiplex Real-time PCR Technology: Enables fast and efficient screening of the six most common JAK2 exon 12 mutations.
- FAM Color Compatibility: Designed for use with real-time PCR instruments supporting FAM color detection and melting curve analysis.
- CE-IVD Certification: Meets European standards for in vitro diagnostic medical devices, ensuring the kit’s reliability and quality.
- Accurate Diagnosis of Polycythemia Vera: Facilitates the detection of JAK2 exon 12 mutations, crucial for diagnosing polycythemia vera in JAK2 V617F-negative patients.
- Rapid and User-Friendly: Simplifies the genetic testing process, enabling quick and efficient mutation screening.
- Guides Clinical Decision-Making: Aids in selecting appropriate diagnostic pathways and therapeutic strategies based on mutation status.
Diagnosis of Polycythemia Vera: Essential for identifying JAK2 exon 12 mutations in patients with JAK2 V617F-negative erythrocytosis, aiding in the diagnosis of polycythemia vera.
- Mutation Coverage: Targets the six most prevalent mutations on exon 12 of the JAK2 gene.
- Technology: Utilizes allele-specific and multiplex real-time PCR for efficient and accurate mutation detection.
- Compatibility: Compatible with FAM color real-time PCR instruments capable of performing melting curve analysis.
- Certification: Carries the CE-IVD mark, indicating compliance with EU regulations for in vitro diagnostic use.
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