MLL-AF4 t(4;11) Detection Kit
£681.00
The MLL-AF4 t(4;11) Detection Kit utilizes one-step RT-qPCR technology for the rapid, accurate detection of the MLL-AF4 fusion gene, resulting from the translocation between chromosomes 4 and 11. This genetic marker is particularly associated with acute lymphoblastic leukemia (ALL) and some cases of acute myeloid leukemia (AML). Offering superior analytical sensitivity (log4 reduction) and accurate relative quantitation through multiplex PCR, this CE-IVD certified kit is compatible with FAM and VIC/HEX dual-color real-time PCR instruments, making it a vital tool for diagnosing leukemia, which is characterized by the overproduction of abnormal white blood cells.
The MLL-AF4 t(4;11) Detection Kit utilizes one-step RT-qPCR technology for the rapid, accurate detection of the MLL-AF4 fusion gene, resulting from the translocation between chromosomes 4 and 11. This genetic marker is particularly associated with acute lymphoblastic leukemia (ALL) and some cases of acute myeloid leukemia (AML). Offering superior analytical sensitivity (log4 reduction) and accurate relative quantitation through multiplex PCR, this CE-IVD certified kit is compatible with FAM and VIC/HEX dual-color real-time PCR instruments, making it a vital tool for diagnosing leukemia, which is characterized by the overproduction of abnormal white blood cells.
- Superior Analytical Sensitivity: Delivers a log4 reduction in detection sensitivity, enabling the identification of low levels of the MLL-AF4 fusion transcript.
- Fast and User-Friendly: Simplifies the testing process with one-step RT-qPCR technology, reducing the time to results.
- Multiplex PCR: Allows for accurate relative quantitation by comparing fusion transcripts against ABL1 gene expression, enhancing diagnostic precision.
- Instrument Compatibility: Designed for use with FAM and VIC/HEX dual-color real-time PCR instruments, ensuring versatility across laboratory settings.
- CE-IVD Certification: Meets European standards for in vitro diagnostic medical devices, ensuring the kit’s quality and reliability for clinical use.
- Efficient Leukemia Diagnosis: Streamlines the detection of the MLL-AF4 fusion gene, crucial for diagnosing and monitoring ALL and some AML cases.
- High Sensitivity and Accuracy: Ensures reliable detection and quantitation of the fusion gene, even at low levels, facilitating early diagnosis and treatment.
- Ease of Use: The one-step RT-qPCR approach reduces the complexity and time required for testing, making it accessible for routine diagnostic purposes.
Leukemia Diagnosis and Monitoring: Specifically targets the MLL-AF4 t(4;11) fusion gene for patients suspected of or diagnosed with acute lymphoblastic leukemia (ALL) or acute myeloid leukemia (AML), playing a vital role in diagnosis, prognosis, and treatment monitoring.
- Technology: Employs one-step RT-qPCR with multiplex PCR for the detection and relative quantitation of the MLL-AF4 fusion transcript.
- Sensitivity: Features superior analytical sensitivity (log4 reduction) for detecting minimal levels of the target gene.
- Compatibility: Compatible with FAM and VIC/HEX dual-color real-time PCR instruments.
- Certification: Carries the CE-IVD mark, indicating compliance with EU regulations for in vitro diagnostic use.
Why Choose Clent
We strive to enable our customers to focus on the results of their work, rather than the tools they use. Need to speak with a member of our team? Get in touch today.
