The geneMAP™ Celiac Detection Kit offers a targeted approach for the genetic detection of celiac disease predisposition by identifying key HLA alleles (DQ2, DQ8, and DR4). Using allele-specific PCR technology, this kit enables precise identification of genetic markers associated with celiac disease in a straightforward testing procedure.
- Allele-Specific PCR Technology: Ensures accurate detection of the HLA-DQ2, DQ8, and DR4 alleles, crucial for celiac disease predisposition.
- Instrument Compatibility: Fully compatible with all real-time PCR instruments capable of melting curve analysis, offering broad usability across different laboratory settings.
- CE-IVD Certification: Meets the stringent requirements of the European In Vitro Diagnostic Directive, ensuring quality and reliability for diagnostic use.
- Precision and Accuracy: By employing allele-specific PCR, the kit provides highly accurate results, essential for the reliable diagnosis of celiac disease susceptibility.
- Ease of Use: Designed for simplicity, the kit enables a straightforward testing process, making it accessible for various laboratory environments.
- Broad Compatibility: The ability to work with any real-time PCR instrument capable of melting curve analysis significantly increases the kit’s versatility and application range.
- Genetic Testing for Celiac Disease: Specifically designed to identify individuals at genetic risk for celiac disease by detecting the presence of HLA-DQ2, DQ8, and DR4 alleles. This is critical for the diagnosis and management of celiac disease, a condition triggered by gluten ingestion in genetically susceptible individuals.
- Technology: Allele-specific PCR for the detection of HLA-DQ2 (HLA-DQA105 and DQB102), HLA-DQ8 (HLA-DQA103 DQB103:02), and the associated HLA-DR4 allele.
- Compatibility: Usable with all real-time PCR instruments that support melting curve analysis.
- Certification: CE-IVD marked, validating its use as an in vitro diagnostic tool within the European Union.
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