BCRSCR-RT48
BCR-ABL1 (p190, p210, p230) Screening Kit
Quantity: 48 Tests
£1,852.00
The geneMAP™ BCR-ABL1 (p190, p210, p230) Screening assay for screening and genotyping of 3 most common (p190, p210 and p230) fusion transcripts in one PCR well with its one-step Quadruplex technology.
The geneMAP™ BCR-ABL1 (p190, p210, p230) Screening assay for screening and genotyping of 3 most common (p190, p210 and p230) fusion transcripts in one PCR well with its one-step Quadruplex technology.
- Superior Analytical Sensitivity and Specificity: Utilizes Quadruplex PCR technology to provide high levels of sensitivity and specificity in detecting BCR-ABL1 fusion transcripts.
- Fast and Easy to Use: Employs One Step RT-qPCR Technology, simplifying the workflow and reducing the time to results.
- Accurate Screening and Genotyping: Enables Multiplex PCR for simultaneous detection and genotyping of the most common fusion transcripts of BCR-ABL1/ABL1 (p210, p190, & p230) in a single PCR well.
- Compatibility: Works with real-time PCR instruments that detect FAM, VIC/HEX, ROX, and CY5, accommodating a broad range of laboratory equipment.
- CE-IVD Marked: Certified for in vitro diagnostic use in the European Union, ensuring compliance with health and safety standards.
- Enhanced Detection Capabilities: The kit’s Quadruplex PCR approach ensures highly sensitive and specific detection of the BCR-ABL1 fusion genes.
- Streamlined Process: The use of One Step RT-qPCR Technology significantly simplifies the testing procedure, making it quicker and easier for laboratory personnel.
- Comprehensive Analysis: Capable of detecting and differentiating between the three main isoforms of the BCR-ABL1 fusion gene in a single assay, providing valuable information for diagnosis and treatment planning.
- Broad Instrument Compatibility: Designed to be used with a wide range of PCR instruments, increasing its utility in diverse laboratory settings.
- Disease Identification and Monitoring: Specifically designed for the screening and genotyping of the BCR-ABL1 fusion transcripts associated with various hematopoietic disorders, including:
- Chronic Myeloid Leukemia (CML)
- Acute Lymphoblastic Leukemia (ALL)
- Acute Myeloid Leukemia (AML)
- Research and Clinical Use: Ideal for detecting the presence of the Philadelphia chromosome (Ph chromosome) and identifying the specific BCR-ABL1 isoforms (p190, p210, p230) in hematopoietic stem cells.
- Technology: One Step RT-qPCR with Quadruplex PCR for Multiplex detection.
- Target Genes: Screens and genotypes for BCR-ABL1 fusion transcripts (p190, p210, and p230).
- Detection Channels: Compatible with FAM, VIC/HEX, ROX, and CY5 fluorescence markers.
- Certification: CE-IVD, ensuring quality and regulatory compliance for use in diagnostic applications.
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