CBFB-MYH11 Inv(16) Detection Kit
£681.00
The CBFB-MYH11 Inv(16) Detection Kit utilizes one-step RT-qPCR technology for the rapid and accurate detection of the CBFB-MYH11 fusion gene, resulting from the inversion of chromosome 16 (Inv(16)). This genetic marker is significantly associated with a subtype of acute myeloid leukemia (AML) known for its distinct clinical and pathological features. Offering superior analytical sensitivity (log4 reduction) and accurate relative quantitation through multiplex PCR, this CE-IVD certified kit is compatible with FAM and VIC/HEX dual-color real-time PCR instruments, making it a critical tool for the diagnosis and monitoring of leukemia.
The CBFB-MYH11 Inv(16) Detection Kit utilizes one-step RT-qPCR technology for the rapid and accurate detection of the CBFB-MYH11 fusion gene, resulting from the inversion of chromosome 16 (Inv(16)). This genetic marker is significantly associated with a subtype of acute myeloid leukemia (AML) known for its distinct clinical and pathological features. Offering superior analytical sensitivity (log4 reduction) and accurate relative quantitation through multiplex PCR, this CE-IVD certified kit is compatible with FAM and VIC/HEX dual-color real-time PCR instruments, making it a critical tool for the diagnosis and monitoring of leukemia.
- Superior Analytical Sensitivity: Delivers a log4 reduction in detection sensitivity, enabling the identification of low levels of the CBFB-MYH11 fusion transcript.
- Fast and User-Friendly: Simplifies the testing process with one-step RT-qPCR technology, reducing time to results.
- Multiplex PCR: Allows for accurate relative quantitation by comparing fusion transcripts against ABL1 gene expression, enhancing diagnostic precision.
- Instrument Compatibility: Designed for use with FAM and VIC/HEX dual-color real-time PCR instruments, ensuring versatility across laboratory settings.
- CE-IVD Certification: Meets European standards for in vitro diagnostic medical devices, ensuring the kit’s quality and reliability for clinical use.
- Efficient Leukemia Diagnosis: Streamlines the detection of the CBFB-MYH11 fusion gene, crucial for diagnosing and monitoring the Inv(16) subtype of AML.
- High Sensitivity and Accuracy: Ensures reliable detection and quantitation of the fusion gene, even at minimal levels, facilitating early diagnosis and treatment planning.
- Ease of Use: The one-step RT-qPCR approach reduces the complexity and duration of the testing procedure, enabling routine diagnostic use.
Leukemia Diagnosis and Monitoring: Specifically targets the CBFB-MYH11 Inv(16) fusion gene for patients suspected of or diagnosed with the Inv(16) subtype of acute myeloid leukemia (AML), playing a vital role in diagnosis, prognosis, and treatment monitoring strategies.
- Technology: Employs one-step RT-qPCR with multiplex PCR for the detection and relative quantitation of the CBFB-MYH11 fusion transcript.
- Sensitivity: Features superior analytical sensitivity (log4 reduction) for detecting low levels of the target gene.
- Compatibility: Compatible with FAM and VIC/HEX dual-color real-time PCR instruments.
- Certification: Carries the CE-IVD mark, indicating compliance with EU regulations for in vitro diagnostic use.
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