TEL-AML1 t(12;21) Detection Kit
£681.00
The TEL-AML1 t(12;21) Detection Kit leverages one-step RT-qPCR technology for the swift and precise detection of the TEL-AML1 fusion gene, resulting from the translocation between chromosomes 12 and 21. This genetic marker is notably associated with acute lymphoblastic leukemia (ALL), the most common type of leukemia in children. With superior analytical sensitivity (log4 reduction) and accurate relative quantitation through multiplex PCR, this CE-IVD certified kit is compatible with FAM and VIC/HEX dual-color real-time PCR instruments, providing an essential tool for the diagnosis and monitoring of leukemia.
- Superior Analytical Sensitivity: Achieves a log4 reduction, enabling the detection of low levels of the TEL-AML1 fusion transcript.
- One-Step RT-qPCR Technology: Streamlines the testing process, making it both quick and straightforward to execute.
- Multiplex PCR: Facilitates accurate relative quantitation by comparing fusion transcripts to ABL1 gene expression, enhancing diagnostic accuracy.
- Instrument Compatibility: Designed for use with FAM and VIC/HEX dual-color real-time PCR instruments, broadening its utility in various laboratory settings.
- CE-IVD Certification: Meets European standards for in vitro diagnostic medical devices, ensuring the kit’s quality and reliability.
Leukemia Diagnosis and Monitoring: Specifically targets the TEL-AML1 t(12;21) fusion gene for patients suspected of or diagnosed with acute lymphoblastic leukemia (ALL), playing a key role in diagnosis, prognosis, and treatment monitoring strategies.
- Technology: Utilizes one-step RT-qPCR with multiplex PCR for the detection and relative quantitation of the TEL-AML1 fusion transcript.
- Sensitivity: Features superior analytical sensitivity (log4 reduction) for detecting low levels of the target gene.
- Compatibility: Compatible with FAM and VIC/HEX dual-color real-time PCR instruments.
- Certification: Carries the CE-IVD mark, indicating compliance with EU regulations for in vitro diagnostic use.
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