PAI-RT50

PAI-1 4G/5G Mutation Detection Kit

Quantity: 50 Tests

£326.00

The Plasminogen Activator Inhibitor 1 (PAI-1/SERPINE1) 4G/5G Mutation Detection Kit is tailored for the identification of the 4G allele in the PAI-1 gene, a mild risk factor for venous thromboembolism (VTE) and Myocardial Infarction (MI). Utilizing multiplex RT-PCR technology, this kit simplifies the detection process of this specific genetic variation, contributing to a comprehensive assessment of thrombophilia risk.

The Plasminogen Activator Inhibitor 1 (PAI-1/SERPINE1) 4G/5G Mutation Detection Kit is tailored for the identification of the 4G allele in the PAI-1 gene, a mild risk factor for venous thromboembolism (VTE) and Myocardial Infarction (MI). Utilizing multiplex RT-PCR technology, this kit simplifies the detection process of this specific genetic variation, contributing to a comprehensive assessment of thrombophilia risk.

  • Ready to Reaction Mix: Minimizes preparation time, enhancing ease of use for laboratory staff.
  • Accurate Results: Includes controls for both homozygous and heterozygous mutations to ensure the reliability of test outcomes.
  • Dual Color Compatibility: Compatible with real-time PCR instruments that detect FAM and VIC/HEX, enabling simultaneous detection of multiple genetic markers.
  • CE-IVD Certification: Adheres to European standards for in vitro diagnostic medical devices, ensuring the kit’s quality and dependability.
  • Simplified Testing Procedure: The kit’s pre-prepared reaction mix streamlines the testing process, allowing for rapid and efficient detection.
  • Dependable Diagnostics: By including specific controls, the kit offers accurate results critical for genetic risk assessment.
  • Versatile Instrument Compatibility: Designed for use with a wide array of dual-color real-time PCR instruments, increasing its usability.
  • Certified Quality: The CE-IVD mark confirms that the kit complies with EU regulations, providing a high standard of diagnostic performance.

Genetic Risk Assessment for Thrombophilia and Cardiovascular Diseases: Primarily aimed at detecting the PAI-1 4G/5G polymorphism, this kit serves as an important tool for evaluating genetic predispositions to thrombophilia, VTE, and myocardial infarction.

  • Technology: Employs multiplex RT-PCR for the targeted detection of the PAI-1 4G/5G polymorphism, among other genetic risk factors for thrombophilia.
  • Compatibility: Suitable for FAM and VIC/HEX dual-color real-time PCR instruments.
  • Controls Included: Features controls for both homozygous and heterozygous conditions to validate assay accuracy.
  • Certification: Carries the CE-IVD marking, indicating its suitability for in vitro diagnostic use within the European Union.

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