BCRSCR-RT48
BCR-ABL1 (p190, p210, p230) Screening Kit
Quantity: 48 Tests
£1,852.00
The geneMAP™ BCR-ABL1 Screening Kit is intended for detection of P190BCR-ABL1 (e1a2), P210BCR-ABL1 (b2a2 & b3a2) and P230BCR-ABL1 (e19a2) fusion transcripts in bone marrow or peripheral blood samples of patients who have been diagnosed with Acute Lymphoblastic Leukemia (ALL) or Chronic Myeloid Leukemia (CML).
The Kit can distinguish between the p190 BCR-ABL1, p210 BCR-ABL1 & p230 BCR-ABL1.
- Superior Analytical Sensitivity and Specificity: Utilizes Quadruplex PCR technology to provide high levels of sensitivity and specificity in detecting BCR-ABL1 fusion transcripts.
- Fast and Easy to Use: Employs One Step RT-qPCR Technology, simplifying the workflow and reducing the time to results.
- Accurate Screening and Genotyping: Enables Multiplex PCR for simultaneous detection and genotyping of the most common fusion transcripts of BCR-ABL1/ABL1 (p210, p190, & p230) in a single PCR well.
- Compatibility: Works with real-time PCR instruments that detect FAM, VIC/HEX, ROX, and CY5, accommodating a broad range of laboratory equipment.
- CE-IVD Marked: Certified for in vitro diagnostic use in the European Union, ensuring compliance with health and safety standards.
- Disease Identification and Monitoring: Specifically designed for the screening and genotyping of the BCR-ABL1 fusion transcripts associated with various hematopoietic disorders, including:
- Chronic Myeloid Leukemia (CML)
- Acute Lymphoblastic Leukemia (ALL)
- Acute Myeloid Leukemia (AML)
- Research and Clinical Use: Ideal for detecting the presence of the Philadelphia chromosome (Ph chromosome) and identifying the specific BCR-ABL1 isoforms (p190, p210, p230) in hematopoietic stem cells.
- Technology: One Step RT-qPCR with Quadruplex PCR for Multiplex detection.
- Target Genes: Screens and genotypes for BCR-ABL1 fusion transcripts (p190, p210, and p230).
- Detection Channels: Compatible with FAM, VIC/HEX, ROX, and CY5 fluorescence markers.
- Certification: CE-IVD, ensuring quality and regulatory compliance for use in diagnostic applications.
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