CALR-RT25
CALR Mutation Screening Kit
Quantity: 25 Tests
£1,333.00
The geneMAP™ CALR Screening Kit is a qualitative in vitro assay for the detection of 36 CALR somatic mutations from human genomic DNA of subjects suspected of myeloproliferative neoplasms (MPN) and also allows the identification of the two major CALR mutations (Type 1 and Type 2).
- Allele Specific PCR: Ensures high specificity and sensitivity for CALR mutation detection.
- Multiplex Real-time PCR Technology: Facilitates the fast and efficient analysis of CALR gene mutations.
- Compatibility: Designed for use with FAM, VIC/HEX two-color real-time PCR instruments, offering flexibility in laboratory settings.
- Research Use Only:
Research in Myeloproliferative Neoplasms: Critical for studying the role of CALR mutations in the pathogenesis and prognosis of ET and PMF, and for distinguishing these conditions from benign reactive processes and other hematologic malignancies.
- Mutation Coverage: Targets a variety of insertion or deletion mutations in exon 9 of the CALR gene, including type-1 (52 bp deletion) and type-2 (5 bp insertion) mutations, among others.
- Technology: Utilizes allele-specific and multiplex real-time PCR for efficient and accurate mutation detection.
- Compatibility: Suitable for use with FAM and VIC/HEX two-color real-time PCR instruments.
- Usage: Designated for research purposes only, not approved for diagnostic use.
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