MPL W515A/L/K/R Mutation Detection Kit
£889.00
The geneMAP™ MPL W515A/L/K/R Mutation Detection Kit is engineered for the high-precision detection of clinically significant mutations within the MPL gene, specifically W515A, W515L, W515K, and W515R. Utilizing allele-specific PCR and multiplex real-time PCR technology, this kit offers superior analytical sensitivity and specificity. It’s designed for compatibility with FAM and VIC/HEX two-color real-time PCR instruments and is CE-IVD certified. This kit serves as a critical tool for diagnosing and understanding the genetic basis of myeloproliferative neoplasms (MPNs), including polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF), especially among patients who are JAK2 V617F-negative.
The geneMAP™ MPL W515A/L/K/R Mutation Detection Kit is engineered for the high-precision detection of clinically significant mutations within the MPL gene, specifically W515A, W515L, W515K, and W515R. Utilizing allele-specific PCR and multiplex real-time PCR technology, this kit offers superior analytical sensitivity and specificity. It's designed for compatibility with FAM and VIC/HEX two-color real-time PCR instruments and is CE-IVD certified. This kit serves as a critical tool for diagnosing and understanding the genetic basis of myeloproliferative neoplasms (MPNs), including polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF), especially among patients who are JAK2 V617F-negative.
- Allele Specific PCR: Ensures high specificity and sensitivity in detecting MPL mutations.
- Multiplex Real-time PCR Technology: Facilitates the simultaneous detection of 7 clinically relevant MPL mutations, enhancing diagnostic efficiency.
- Compatibility: Works seamlessly with FAM, VIC/HEX two-color real-time PCR instruments, offering broad usability.
- CE-IVD Certification: Meets European standards for in vitro diagnostic medical devices, ensuring reliability and quality in diagnostics.
- Accurate Mutation Detection: Provides reliable identification of specific MPL mutations, crucial for the diagnosis and prognosis of MPNs.
- Rapid and User-Friendly: Designed for ease of use, the kit allows for quick and efficient mutation screening, facilitating timely decision-making in clinical settings.
- Comprehensive Analysis: With the capability to detect multiple MPL mutations, this kit offers a comprehensive approach to understanding the genetic landscape of MPN patients.
- Diagnosis and Prognosis of MPNs: Essential for identifying MPL mutations in patients with polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF), particularly those who are negative for the JAK2 V617F mutation.
- Genetic Screening: Supports genetic screening efforts in populations at risk or suspected of having MPNs, aiding in early detection and intervention.
- Mutation Coverage: Detects MPL W515A, W515L, W515K, and W515R mutations among others, addressing the most clinically relevant variations.
- Technology: Utilizes allele-specific and multiplex real-time PCR for efficient and accurate mutation detection.
- Compatibility: Suitable for use with FAM and VIC/HEX two-color real-time PCR instruments.
- Certification: Carries the CE-IVD marking, indicating its approved use within the European Union for in vitro diagnostics.
Why Choose Clent
We strive to enable our customers to focus on the results of their work, rather than the tools they use. Need to speak with a member of our team? Get in touch today.
