NPM-RT25
NPM1 (MutA,B,C&D) Mutation Detection Kit
Quantity: 25 Tests
£1,333.00
NPM1 Mutation detection Kit is intended for detection and mutation ratio calculation of Nucleophosmin-1 (NPM1) A, B, C and D mutations from peripheric blood and bone marrow from Acute Myeloid Leukemia patients.
The kit can not distinguish between the MutA, MutB, MutC & MutD.
The results obtained are intended to be used as an aid to monitor efficacy of treatment in patients undergoing therapy, and for minimal residual disease (MRD) follow-up to monitor disease relapse.
- Allele Specific PCR: Ensures high specificity and sensitivity in detecting NPM1 mutations (MutA, B, C, and D).
- Multiplex Real-time PCR Technology: Enables fast and efficient analysis of multiple NPM1 mutations, facilitating timely clinical decision-making.
- Instrument Compatibility: Works seamlessly with FAM and VIC/HEX two-color real-time PCR instruments, providing flexibility in laboratory use.
- CE-IVD Certification: Meets European standards for in vitro diagnostic medical devices, affirming the kit’s reliability and quality.
- Diagnosis and Prognosis of AML: Essential for identifying AML patients with NPM1 mutations (MutA, B, C, and D), informing prognosis and tailoring treatment approaches based on genetic findings.
- Mutation Coverage: Targets the four most prevalent mutations on the NPM1 gene (MutA, B, C, and D), addressing the most clinically significant variations.
- Technology: Utilizes allele-specific and multiplex real-time PCR for efficient and accurate mutation detection.
- Compatibility: Compatible with FAM and VIC/HEX two-color real-time PCR instruments.
- Certification: Carries the CE-IVD mark, indicating compliance with EU regulations for in vitro diagnostic use.
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