The geneMAP™ PD-L1 Expression Analysis Kit is designed for the rapid and accurate assessment of PD-L1 gene expression using multiplex real-time PCR technology combined with TaqMan Probe technology. This kit, intended for research use only (RUO), is compatible with FAM and VIC/HEX two-color real-time PCR instruments. It enables the quantitative analysis of PD-L1 expression, a critical factor in predicting the efficacy of immunotherapies in advanced non-small cell lung cancer (NSCLC) and other malignancies where PD-L1 expression levels are associated with clinical outcomes like overall survival and response to treatments such as nivolumab versus docetaxel.
- Fast and User-Friendly: Simplifies the process of PD-L1 expression analysis, allowing for quick and efficient testing.
- Accurate Expression Analysis: Utilizes TaqMan Probe technology for precise quantification of PD-L1 expression levels.
- Compatible Instrumentation: Designed for use with FAM, VIC/HEX two-color real-time PCR instruments, enhancing its utility across various laboratory settings.
- Immunotherapy Research: Critical for studies exploring the association between PD-L1 expression levels and the efficacy of immunotherapeutic agents in NSCLC and other cancers.
- Clinical Efficacy Endpoints Research: Enables research into the relationship between PD-L1 expression and clinical outcomes such as overall survival and progression-free survival.
- Technology: Combines multiplex real-time PCR with TaqMan Probe technology for accurate PD-L1 expression analysis.
- Compatibility: Suitable for use with FAM and VIC/HEX two-color real-time PCR instruments.
- Usage: Intended for research use only, not for diagnostic procedures.
- Clinical Relevance: Assists in understanding PD-L1’s role in predicting responses to immunotherapy, particularly in advanced NSCLC.
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