RUNX1-RUNX1T1 t(8;21) Detection Kit
£681.00
The RUNX1-RUNX1T1 t(8;21) Detection Kit utilizes one-step RT-qPCR technology for the fast and accurate detection of the RUNX1-RUNX1T1 fusion gene, resulting from the translocation between chromosomes 8 and 21. This genetic anomaly is notably associated with acute myeloid leukemia (AML). Offering superior analytical sensitivity (log4 reduction) and accurate relative quantitation through multiplex PCR, this CE-IVD certified kit is compatible with FAM and VIC/HEX dual-color real-time PCR instruments, providing a crucial tool for the diagnosis and monitoring of leukemia, a disease characterized by the overproduction of abnormal white blood cells.
- Superior Analytical Sensitivity: Delivers a log4 reduction, enabling the detection of low levels of the RUNX1-RUNX1T1 fusion transcript.
- Fast and User-Friendly: Simplifies the testing process with one-step RT-qPCR technology, reducing time to results.
- Multiplex PCR: Allows for accurate relative quantitation by comparing fusion transcripts to ABL1 gene expression, enhancing diagnostic precision.
- Instrument Compatibility: Designed for use with FAM and VIC/HEX dual-color real-time PCR instruments, ensuring versatility across laboratory settings.
- CE-IVD Certification: Meets European standards for in vitro diagnostic medical devices, ensuring the kit’s quality and reliability for clinical use.
Leukemia Diagnosis and Monitoring: Specifically targets the RUNX1-RUNX1T1 t(8;21) fusion gene for patients suspected of or diagnosed with acute myeloid leukemia (AML), playing a vital role in diagnosis, prognosis, and treatment monitoring.
- Technology: Employs one-step RT-qPCR with multiplex PCR for the detection and relative quantitation of the RUNX1-RUNX1T1 fusion transcript.
- Sensitivity: Features superior analytical sensitivity (log4 reduction) for detecting minimal levels of the target gene.
- Compatibility: Compatible with FAM and VIC/HEX dual-color real-time PCR instruments.
- Certification: Carries the CE-IVD mark, indicating compliance with EU regulations for in vitro diagnostic use.
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