RUNX1-RUNX1T1 t(8;21) Detection Kit
£681.00
The RUNX1-RUNX1T1 t(8;21) Detection Kit utilizes one-step RT-qPCR technology for the fast and accurate detection of the RUNX1-RUNX1T1 fusion gene, resulting from the translocation between chromosomes 8 and 21. This genetic anomaly is notably associated with acute myeloid leukemia (AML). Offering superior analytical sensitivity (log4 reduction) and accurate relative quantitation through multiplex PCR, this CE-IVD certified kit is compatible with FAM and VIC/HEX dual-color real-time PCR instruments, providing a crucial tool for the diagnosis and monitoring of leukemia, a disease characterized by the overproduction of abnormal white blood cells.
- Superior Analytical Sensitivity: Delivers a log4 reduction, enabling the detection of low levels of the RUNX1-RUNX1T1 fusion transcript.
- Fast and User-Friendly: Simplifies the testing process with one-step RT-qPCR technology, reducing time to results.
- Multiplex PCR: Allows for accurate relative quantitation by comparing fusion transcripts to ABL1 gene expression, enhancing diagnostic precision.
- Instrument Compatibility: Designed for use with FAM and VIC/HEX dual-color real-time PCR instruments, ensuring versatility across laboratory settings.
- CE-IVD Certification: Meets European standards for in vitro diagnostic medical devices, ensuring the kit’s quality and reliability for clinical use.
Leukemia Diagnosis and Monitoring: Specifically targets the RUNX1-RUNX1T1 t(8;21) fusion gene for patients suspected of or diagnosed with acute myeloid leukemia (AML), playing a vital role in diagnosis, prognosis, and treatment monitoring.
- Technology: Employs one-step RT-qPCR with multiplex PCR for the detection and relative quantitation of the RUNX1-RUNX1T1 fusion transcript.
- Sensitivity: Features superior analytical sensitivity (log4 reduction) for detecting minimal levels of the target gene.
- Compatibility: Compatible with FAM and VIC/HEX dual-color real-time PCR instruments.
- Certification: Carries the CE-IVD mark, indicating compliance with EU regulations for in vitro diagnostic use.
- Superior Analytical Sensitivity: Delivers a log4 reduction, enabling the detection of low levels of the RUNX1-RUNX1T1 fusion transcript.
- Fast and User-Friendly: Simplifies the testing process with one-step RT-qPCR technology, reducing time to results.
- Multiplex PCR: Allows for accurate relative quantitation by comparing fusion transcripts to ABL1 gene expression, enhancing diagnostic precision.
- Instrument Compatibility: Designed for use with FAM and VIC/HEX dual-color real-time PCR instruments, ensuring versatility across laboratory settings.
- CE-IVD Certification: Meets European standards for in vitro diagnostic medical devices, ensuring the kit’s quality and reliability for clinical use.
Leukemia Diagnosis and Monitoring: Specifically targets the RUNX1-RUNX1T1 t(8;21) fusion gene for patients suspected of or diagnosed with acute myeloid leukemia (AML), playing a vital role in diagnosis, prognosis, and treatment monitoring.
- Technology: Employs one-step RT-qPCR with multiplex PCR for the detection and relative quantitation of the RUNX1-RUNX1T1 fusion transcript.
- Sensitivity: Features superior analytical sensitivity (log4 reduction) for detecting minimal levels of the target gene.
- Compatibility: Compatible with FAM and VIC/HEX dual-color real-time PCR instruments.
- Certification: Carries the CE-IVD mark, indicating compliance with EU regulations for in vitro diagnostic use.
Download essential technical information for this product.
Why Choose Clent
We strive to enable our customers to focus on the results of their work, rather than the tools they use. Need to speak with a member of our team? Get in touch today.
