SMT-RT50
Somatic Mutation (JAK2 V617F) Detection Kit
Quantity: 50 Tests
£889.00
The geneMAP™ Somatic Mutation Detection Kit is intended for the detection and quantification of JAK2 exon 14 V617F/c.1849G>T mutation in DNA extracted from peripheral blood. The kit can be used as an aid in the evaluation of suspected Philadelphia (Ph) chromosome-negative myeloproliferative neoplasm (MPN) and molecular disease monitoring in MPN patients. The absence of the JAK2 V617F/c.1849G>T mutation does not exclude the presence of other JAK2 mutations.
Somatic Mutation JAK2 V617F Detection Kit
- Quantitative detection of JAK2 exon 14, V617F mutation.
- Superior analytical sensitivity and specifity with Allele Spesfic PCR.
- Fast and Easy use with Multiplex Realtime PCR Technology.
- Limit of Detection 0.018 %, with a 95% confidence.
- Automatic analysis with geneMAP viewer (for CFX96TM / BIO-RAD).
RUO
- Research and Clinical Diagnostics: Ideal for detecting somatic mutations in genes associated with cancer, genetic disorders, and other diseases.
- Genetic Screening: Can be used for screening populations or individuals at risk of genetic mutations, aiding in early detection and intervention strategies.
- Technology: ASO-Realtime-PCR for allele-specific amplification and analysis.
- Sensitivity: Detects mutations with a minimum frequency of 0.5%.
- Compatibility: Designed for use with all real-time PCR instruments capable of detecting FAM and VIC/HEX signals.
- Kit Contents: Includes 2 X Master Mix, Mutation Primer Probe Mix, ddH2O, and Positive Control, with volumes specified for complete analysis.
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