TCF3/PBX1 t(1;19) Detection Kit
£681.00
The TCF3/PBX1 t(1;19) Detection Kit employs advanced one-step RT-qPCR technology for the rapid and accurate detection of the TCF3/PBX1 fusion gene, which results from the translocation between chromosomes 1 and 19. This genetic marker is commonly associated with certain types of leukemia, including acute lymphoblastic leukemia (ALL). With superior analytical sensitivity (log4 reduction) and accurate relative quantitation through multiplex PCR, this CE-IVD certified kit is compatible with FAM and VIC/HEX dual-color real-time PCR instruments. It serves as a crucial diagnostic tool for leukemia, a malignancy characterized by the overproduction of abnormal white blood cells in the bone marrow, leading to serious health complications.
The TCF3/PBX1 t(1;19) Detection Kit employs advanced one-step RT-qPCR technology for the rapid and accurate detection of the TCF3/PBX1 fusion gene, which results from the translocation between chromosomes 1 and 19. This genetic marker is commonly associated with certain types of leukemia, including acute lymphoblastic leukemia (ALL). With superior analytical sensitivity (log4 reduction) and accurate relative quantitation through multiplex PCR, this CE-IVD certified kit is compatible with FAM and VIC/HEX dual-color real-time PCR instruments. It serves as a crucial diagnostic tool for leukemia, a malignancy characterized by the overproduction of abnormal white blood cells in the bone marrow, leading to serious health complications.
- Superior Analytical Sensitivity: Achieves a log4 reduction in detection sensitivity, enabling the identification of low levels of the TCF3/PBX1 fusion transcript.
- One-Step RT-qPCR Technology: Streamlines the testing process, making it both quick and straightforward to execute.
- Multiplex PCR: Facilitates accurate relative quantitation by comparing fusion transcripts against ABL1 gene expression, enhancing diagnostic accuracy.
- Instrument Compatibility: Designed for use with FAM and VIC/HEX dual-color real-time PCR instruments, broadening its applicability in various laboratory environments.
- CE-IVD Certification: Adheres to European standards for in vitro diagnostic medical devices, ensuring the kit’s reliability and quality.
Leukemia Diagnosis and Monitoring: Specifically targets the TCF3/PBX1 t(1;19) fusion gene for patients suspected of or diagnosed with acute lymphoblastic leukemia (ALL), playing a key role in diagnosis, prognosis, and treatment monitoring strategies.
- Technology: Utilizes one-step RT-qPCR with multiplex PCR for the detection and relative quantitation of the TCF3/PBX1 fusion transcript.
- Sensitivity: Features superior analytical sensitivity (log4 reduction) for detecting low levels of the target gene.
- Compatibility: Compatible with FAM and VIC/HEX dual-color real-time PCR instruments.
- Certification: Carries the CE-IVD mark, indicating compliance with EU regulations for in vitro diagnostic use.
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