WT1 Expression Analysis Kit
£889.00
The geneMAP™ WT1 Expression Analysis Kit is designed for the accurate assessment of WT1 gene expression levels using multiplex real-time PCR technology and TaqMan Probe technology. This kit, which is compatible with FAM and VIC/HEX two-color real-time PCR instruments, is intended for research use only (RUO). It plays a crucial role in studying the WT1 gene’s behavior as both a tumor suppressor and an oncogene in various leukemias, particularly in acute myeloid leukemia (AML), where WT1 expression levels have been identified as a potential prognostic marker.
The geneMAP™ WT1 Expression Analysis Kit is designed for the accurate assessment of WT1 gene expression levels using multiplex real-time PCR technology and TaqMan Probe technology. This kit, which is compatible with FAM and VIC/HEX two-color real-time PCR instruments, is intended for research use only (RUO). It plays a crucial role in studying the WT1 gene's behavior as both a tumor suppressor and an oncogene in various leukemias, particularly in acute myeloid leukemia (AML), where WT1 expression levels have been identified as a potential prognostic marker.
- Multiplex Real-time PCR Technology: Facilitates fast and efficient analysis of WT1 expression levels.
- TaqMan Probe Technology: Ensures accurate quantification of gene expression with high specificity.
- Instrument Compatibility: Optimized for use with FAM and VIC/HEX two-color real-time PCR instruments, providing flexibility for different laboratory setups.
- RUO Designation: Specified for research purposes, supporting the advancement of leukemia studies and MRD monitoring strategies.
- Accurate WT1 Quantification: Provides reliable data on WT1 expression, crucial for understanding its role in leukemia progression and patient prognosis.
- Rapid and User-Friendly: Streamlines the gene expression analysis process, allowing for quicker experimental cycles and efficient data collection.
- Versatile Research Tool: Aids in identifying alternative markers for MRD in AML, especially in cases lacking known genetic lesions or clonality markers.
- Leukemia Research: Essential for investigating WT1 as a biomarker in leukemia, particularly AML, and its potential as a prognostic indicator and MRD marker.
- Gene Expression Studies: Facilitates comprehensive analysis of WT1 expression patterns across different cell types, contributing to broader understanding of its regulatory functions.
- Technology: Utilizes multiplex real-time PCR combined with TaqMan Probe technology for precise gene expression analysis.
- Compatibility: Suitable for FAM and VIC/HEX two-color real-time PCR instruments.
- Use Case: Intended for research use only, not approved for diagnostic or therapeutic applications.
- WT1 Focus: Targets WT1 gene expression, offering insights into its dual role in cell growth, development, and leukemia pathology.
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